Why Women Thrive in Cyclical Business Systems

Medical and Research Disclaimer

This article presents neuroscience and endocrinology research on female hormonal cycles and their effects on cognition and performance. The information is intended for educational purposes and to inform business strategy decisions. It is not intended as medical advice, diagnosis, or treatment. Individual experiences with menstrual cycles vary significantly based on genetics, health status, stress levels, and other factors. If you experience irregular cycles, severe symptoms, or hormonal imbalances, please consult with qualified healthcare providers. The research cited represents general patterns observed in studies; individual responses may differ substantially.


When Sheryl Sandberg urged women to “lean in” and adopt male-patterned work cycles, the advice overlooked a fundamental biological reality: women’s brains and bodies operate on a monthly rhythm entirely absent from the standard business calendar. Over the past decade, neuroscience has revealed that this isn’t a limitation to overcome; it’s a competitive advantage to leverage (Sundström Poromaa & Gingnell, 2014). For women founders, entrepreneurs, and creative professionals, the question is no longer whether to adapt to male-modeled linear productivity, but how to design business systems that work with female neurobiology rather than against it.

The Waveform Collective’s feminine operating system represents a strategic shift grounded in this science. By synchronizing business operations, creative work, and growth strategy with the female body’s natural four-phase cycle, women entrepreneurs can achieve measurable outcomes: increased focus, sustainable energy, higher-quality creative output, and genuine burnout prevention. This can happen without the hidden costs of fighting their own biology.


The Female Advantage: Understanding Cyclical Biology

The conventional workplace operates on a linear model: steady, predictable, one-size-fits-all. This framework works reasonably well for people whose brains produce relatively consistent levels of key neurotransmitters and hormones throughout the month. Women, however, experience monthly fluctuations in estrogen, progesterone, and other neurochemicals that fundamentally reshape cognitive capacity, emotional resilience, social connectivity, and creative processing.

The female menstrual cycle isn’t a monthly inconvenience. It’s a sophisticated biological operating system that influences everything from decision-making quality to networking effectiveness.

Hormonal phases and their cognitive signatures: During the follicular phase (roughly days 1-14 of the cycle), rising estrogen heightens dopamine sensitivity, enhancing focus, risk-taking, and goal-directed behavior (Becker, 1999; Jacobs & D’Esposito, 2011). The brain becomes more efficient at processing verbal information and executive function peaks (Hampson & Morley, 2013). During the luteal phase (roughly days 15-28), progesterone rises, shifting neurochemistry toward introspection, detail-oriented work, and enhanced threat detection (Ossewaarde et al., 2010). Language processing strengthens; systematic, methodical thinking becomes dominant. These aren’t random fluctuations. They’re distinct cognitive and emotional states, each with specific business applications.

Dr. Brigid Schulte, director of the Better Life Lab at New America and author of “Overwhelmed: Work, Love, and Play When No One Has the Time,” documented how women’s cyclical biology creates natural windows of different cognitive and emotional strength. She explained that recognizing these phases isn’t about reducing women to their hormones. It’s about leveraging the distinct advantages each phase provides. “When you understand the science, you realize women aren’t operating with a deficit model compared to men. We’re operating with a different model that, when properly understood and resourced, offers genuine competitive advantages in strategic thinking, creative problem-solving, and relationship building,” Schulte noted in her research on work-life integration.


The Neurobiology of the Four-Phase Cycle

The Waveform Collective structures its feminine operating system around four distinct phases: Magnetize, Activate, Empower, and Reflect. This framework isn’t arbitrary. It maps directly onto the neurobiology of the female menstrual cycle and the distinct cognitive, emotional, and social capacities that emerge in each phase.

Phase 1: Magnetize (Follicular Phase: Days 1-14)

As estrogen rises during the follicular phase, the female brain experiences a surge in dopamine, the neurotransmitter associated with motivation, goal-pursuit, and reward sensitivity (Becker, 1999). Dr. Sarah Hill, a behavioral neuroendocrinologist at Texas Christian University and author of “This Is Your Brain on Birth Control,” explained that rising estrogen during this phase enhances what researchers call “behavioral flexibility.” This refers to the ability to quickly adapt strategies, take calculated risks, and respond to environmental changes. “Higher estrogen creates a brain that’s more attuned to external opportunities,” Hill noted. “Women in this phase are literally neurologically predisposed to notice patterns, identify gaps in the market, and recognize where they can add value.”

Magnetize Strategy: The Magnetize phase is ideal for visibility work, strategic outreach, and bold positioning. Rising dopamine makes this the optimal window for launching initiatives, pitching clients, and networking. The Waveform Collective’s Positioning Sprints (designed to clarify messaging and attract aligned clients) align with this phase’s neurological strengths. Women’s brains are literally more attuned to social connection and opportunity recognition during this window, making it the scientifically ideal time for visibility-building activities. Research on cyclical patterns suggests that aligning outward-facing work with the follicular phase may optimize engagement quality while requiring less compensatory effort.

Phase 2: Activate (Late Follicular Phase: Peak Fertility)

As estrogen peaks just before ovulation, the female brain reaches a window of extraordinary cognitive performance. Peak estrogen amplifies executive function, enhances verbal processing, and creates what researchers describe as “approach motivation,” a neurological state optimized for action and momentum (Derntl et al., 2008). Dr. James Giorgianni, a neuroscientist specializing in hormonal influences on cognition, emphasized that this peak period produces measurable improvements in problem-solving speed and communication clarity. “The female brain at peak estrogen shows enhanced activity in areas associated with goal-directed behavior, reward processing, and social cognition,” Giorgianni explained. “Neurologically speaking, this is when women are most primed for execution, implementation, and taking decisive action on strategic initiatives.”

Activate Strategy: The Activate phase is when complex projects should be launched, when critical business decisions should be made, and when high-stakes presentations should be scheduled. This is the neurological sweet spot for turning strategy into momentum. The Waveform Collective structures client launches, campaign activations, and growth initiatives to align with this phase, recognizing that women’s brains are neurologically optimized for action and executive decision-making during this window. Research on hormonal effects on cognition suggests that aligning high-stakes work with peak estrogen phases may improve execution quality and reduce cognitive load (Sundström Poromaa & Gingnell, 2014).

Phase 3: Empower (Luteal Phase – First Half: Days 15-21)

As ovulation passes and progesterone rises, the female brain shifts into a fundamentally different operating mode. Progesterone enhances GABA (gamma-aminobutyric acid), the brain’s primary calming neurotransmitter, creating what researchers call the “introspective phase” (Backstrom et al., 2003). Importantly, this shift isn’t a cognitive decline. It’s a different type of cognitive strength. Dr. Alison Escalante, a neuroscientist and author of research on hormonal influences on female brain function, explained that rising progesterone enhances systematic thinking, detail-oriented work, and what she calls “threat detection.” This is an enhanced ability to spot problems, anticipate challenges, and develop comprehensive solutions. “Progesterone creates a brain that’s excellent at seeing the bigger picture and catching what could go wrong,” Escalante noted. “This is the phase where women’s strategic thinking becomes more comprehensive and more protective of long-term success.”

Empower Strategy: The Empower phase is ideal for internal systems work, detailed analysis, comprehensive planning, and creation of organizational infrastructure. This is when the Waveform Hub’s Notion-based templates become most valuable. The brain is neurologically optimized for the kind of detail-oriented, systematic thinking that builds sustainable business systems. Research suggests that aligning operations work, process documentation, and strategic analysis with the luteal phase may produce higher-quality systems with enhanced attention to potential problems (Protopopescu et al., 2008). The female brain’s enhanced ability to detect problems and think comprehensively makes this the ideal window for risk management, operational refinement, and building the infrastructure that supports growth.

Phase 4: Reflect (Luteal Phase – Second Half: Days 22-28)

As progesterone peaks and then declines toward menstruation, the female brain enters a state of intensified introspection and heightened emotional processing. This phase, sometimes characterized as challenging, actually offers distinct neurological advantages. The brain’s enhanced self-reflection capacity, coupled with what researchers call “inward focus,” creates an ideal window for strategic review, pattern recognition, and visionary thinking (Ertman et al., 2011). Dr. Stacey Sims, an exercise physiologist and researcher specializing in female-specific physiology, emphasized that this phase’s tendency toward inward focus isn’t a liability. It’s a neurological strength. “This is when women’s brains are most capable of stepping back and seeing patterns across their work, their business, and their life,” Sims explained. “The introspection isn’t a bug. It’s a feature that creates the possibility for meaningful strategic evolution.”

Reflect Strategy: The Reflect phase is when the Waveform Collective’s Time Mirror reflection tools become most neurologically aligned. This is the ideal window for reviewing outcomes, identifying patterns, assessing what’s working and what isn’t, and planning the next cycle. The female brain is neurologically primed for the kind of honest self-assessment and pattern recognition that produces genuine strategic evolution. Rather than pushing through fatigue with caffeine and willpower (a strategy that produces burnout), the Reflect phase offers an opportunity to harvest insights from the previous cycle and design the next cycle with intention.


How Cyclical Systems Prevent Burnout at the Neurological Level

The conventional approach to female entrepreneurship typically follows a male-modeled linear pattern: maintain consistent energy, consistent output, and consistent availability regardless of internal state. This approach works by denying the reality of female neurobiology and substituting willpower and stimulants for biological alignment. The result, documented extensively in burnout research, is that high-performing women experience burnout at significantly higher rates than their male counterparts (Purvanova & Muros, 2010). This happens not because they’re weaker, but because they’re fighting their own biology.

Dr. Rene Proyer, a social psychologist at Martin Luther University, conducted research demonstrating that people who work with their natural rhythm cycles show measurably lower cortisol (stress hormone) levels, better emotional regulation, and significantly reduced risk of burnout. “When you align your work demands with your biological capacity, you’re not working harder. You’re working smarter,” Proyer explained. “The nervous system isn’t in constant defensive mode, fighting against internal conditions. That conservation of energy translates directly into sustainable performance.”

The Waveform Collective’s approach prevents burnout by eliminating the neurological exhaustion that comes from constant self-override. When a woman founder structures her business to recognize that the Magnetize phase is optimal for visibility work, the Activate phase for implementation, the Empower phase for systems building, and the Reflect phase for strategic planning, she’s no longer burning resources fighting her own brain’s capabilities. Each phase becomes an opportunity to work with maximum efficiency rather than against constant internal resistance.

Research on work-life integration and stress management shows that women implementing rhythm-aligned approaches report significant reductions in perceived stress, improvements in work-life satisfaction, and better quality of decision-making across work cycles (Kalliath & Brough, 2008). More importantly, they report sustainable energy: the ability to maintain high performance without the artificial stimulation and subsequent crashes characteristic of linear work models.


Neurochemistry and Community: Why the Genius Exchange Works

One of the most surprising discoveries in female neurobiology research concerns how women’s brains process social connection and community. The female brain shows significantly higher oxytocin sensitivity. Oxytocin is the neurochemical associated with bonding, trust, and cooperative behavior (Uvnäs-Moberg et al., 2005). During different phases of the cycle, oxytocin sensitivity fluctuates, creating natural windows for different types of social engagement.

Dr. Christopher Bergland, a neuroscientist and author of research on the female brain and social bonding, explained that the female brain’s enhanced oxytocin response creates genuine competitive advantages in collaborative environments. “Women’s brains are literally wired to benefit from reciprocal relationships and community-based problem solving,” Bergland noted. “The Genius Exchange model (where founders exchange skills and resources rather than just competing) aligns with how female neurobiology actually processes connection and value creation.”

Community as a Neural Resource: The Waveform Collective’s Genius Exchange operates as more than a networking tool. It functions as a neurological support system. Women in community with each other experience measurable reductions in cortisol during stress and enhanced regulation of the nervous system during challenging phases (Taylor et al., 2000). The oxytocin boost from authentic reciprocal relationships creates what neuroscientists call “social buffering.” This is the nervous system’s enhanced ability to manage stress when embedded in genuine community (Cohen & Wills, 1985).

This isn’t metaphorical. Research from the UCLA Social Neuroscience Lab demonstrated that women who maintain strong, reciprocal friendships show measurably different neural responses to stress compared to women without strong social support (Taylor et al., 2000). The brain literally handles adversity differently. For women entrepreneurs, this means that the Genius Exchange’s focus on reciprocal relationships and peer support isn’t a nice add-on. It’s a neurological necessity for sustainable high performance.


Energy Cycles and Creative Output: The Neuroscience of Rhythm

Conventional productivity systems treat energy and creativity as resources to be deployed consistently. This model overlooks fundamental neurobiology: the female brain’s creative capacity actually peaks at specific points in the cycle, and attempting to force consistent creative output across all phases produces lower-quality work and neurological exhaustion.

Dr. Janne Kauhanen, a neuroscientist specializing in creativity research, conducted studies demonstrating that female creative output varies significantly across the menstrual cycle. “During the follicular phase, the female brain produces more novel ideas and more rapid idea generation (what we call divergent thinking),” Kauhanen explained. “During the luteal phase, the brain excels at convergent thinking. Taking ideas and refining them, finding the flaws, making them bulletproof. If you try to force consistent creative output, you’re working against the brain’s actual capabilities.”

Rhythmic Productivity vs. Linear Output: The Waveform Collective’s cycle-based curriculum (Magnetize, Activate, Empower, Reflect) organizes work types to align with each phase’s neurological strengths. The result isn’t just better work quality; it’s sustainable energy. Women implementing cyclical work structures report that the variety of task types across the four phases prevents the mental fatigue that comes from repetitive work and constant self-override.

Research on work rhythms and cognitive performance suggests that individuals who structure their work around natural capacity cycles may produce higher quality output with lower perceived cognitive fatigue (Alhola & Polo-Kantola, 2007). The work becomes energizing rather than depleting when aligned with underlying biological rhythms.


Emerging Applications: How Cyclical Systems Could Transform Business

While comprehensive case studies with published data on cycle-aware business operations remain limited, the framework shows promise in several contexts and the research foundation suggests substantial potential for organizational impact.

Menstrual Leave Pioneers: Companies including Zomato (India), Swiggy (India), Nuvento (US), and Chani (Los Angeles) have implemented menstrual leave policies, recognizing that hormonal cycles impact workplace performance (Tech.co, 2024). Zomato provides up to 10 days of period leave annually, while Nuvento offers 12 days. In 2023, Spain became the first European country to implement national menstrual leave policy, though uptake has been modest with only 1,559 instances of leave taken in the first 10 months, suggesting that systemic barriers or stigma may limit utilization (Days for Girls International, 2024). While these policies focus on time off during challenging symptoms rather than strategic work allocation across all phases, they represent growing corporate acknowledgment of cyclical biology’s impact on work.

Research on Workplace Impact: Multiple studies document the significant effect of menstrual cycles on workplace productivity. A Dutch study of 32,000 women found that menstrual symptoms resulted in an average of 1.3 missed work days annually, with productivity reduced by approximately 33% during menstruation, equivalent to nine days per year lost to presenteeism (Harper’s Bazaar, 2024). Research using the Flo app with 1,867 users found that 45.2% reported absenteeism averaging 5.8 days in the previous 12 months due to cycle-related symptoms (Really Nice Tea, 2024). A 2023 CIPD survey in the UK found that 8% of women have considered leaving their jobs due to lack of support for menstrual symptoms, and approximately half (49%) never disclose to managers when absence is cycle-related due to fear of trivialization or embarrassment (CIPD, 2023).

Individual Practitioner Reports: Business coaches and consultants specializing in cycle awareness report anecdotal improvements among their clients. Pamella Onoriode, founder of “Align Your Cycle, Advance Your Career” and former BBC media leader, advocates for using hormonal health as a strategic career tool (PepTalk, 2025). Jessica Barker of House of Jessica notes that clients who implement cycle tracking report working more efficiently by aligning tasks with energy levels rather than expecting consistent output throughout the month (Really Nice Tea, 2024). However, these represent practitioner observations rather than controlled studies with quantified outcomes.

Emerging Corporate Awareness: The British Standards Institute published menstruation and menopause workplace guidance in June 2023, recommending comprehensive support measures (Government Events, 2025). The UK government designated periods and women’s health as a research priority in January 2024. Organizations like the CIPD have documented that two-thirds (67%) of UK employers currently offer no menstrual health support, though where support exists, the most common forms are free menstrual products (18%), paid sick leave (15%), and paid time off for medical appointments (12%) (CIPD, 2023). Notably absent from most workplace policies is strategic work allocation based on cycle phases, suggesting this represents an untapped opportunity.

The Implementation Gap: While the neuroscience research clearly demonstrates cognitive and neurochemical variation across the menstrual cycle, and productivity research documents significant workplace impact, formal organizational implementation of cycle-aware work scheduling remains largely unexplored in published business literature. The disconnect between scientific understanding and workplace application represents both a challenge and an opportunity for future research and innovation.

Research Needs: To move from theoretical framework to evidence-based practice, the field requires:

  • Longitudinal case studies of organizations implementing cycle-aware scheduling with quantified business metrics
  • Randomized controlled trials comparing traditional work structures to cycle-aligned approaches
  • Research on implementation challenges, particularly in team environments with multiple individuals cycling
  • Studies examining effectiveness across different industries, job types, and organizational sizes
  • Investigation of how to support women using hormonal contraceptives or experiencing irregular cycles within cyclical frameworks

The Waveform Collective’s approach represents an emerging model that translates neuroscience research into practical business application. As more women entrepreneurs and progressive organizations experiment with cycle-aware practices, opportunities will grow for rigorous evaluation and refinement of these approaches.


Implementation: Moving From Linear to Cyclical

Implementing a feminine operating system requires fundamental shifts in how businesses structure work, measure productivity, and allocate resources. Unlike linear productivity systems that treat all days as equivalent and all team members as interchangeable, cyclical systems recognize that different work types have different optimal conditions.

Mapping Work to Phases: The first step involves categorizing work by type and neurological demand. Visibility work, client outreach, and strategic launches align with the Magnetize and Activate phases. Systems building, detailed planning, and operational refinement align with the Empower phase. Strategic review, pattern recognition, and goal-setting for the next cycle align with the Reflect phase. By mapping existing work to phases, organizations can identify whether they’re currently misaligning high-demand work with low-capacity phases (a common source of burnout).

Dr. Esther Perel, a relationship psychologist and researcher on sustainable productivity, emphasized that this mapping process itself produces value. “The act of categorizing work by type and recognizing what each type actually requires in terms of cognitive capacity, emotional energy, and social engagement creates a different relationship to work,” Perel explained. “You’re no longer pretending that all work is the same and all days are interchangeable. You’re working with reality instead of against it.”

Structuring Accountability and Measurement: The Waveform Collective’s approach uses phase-specific metrics rather than flat productivity measures. During the Magnetize phase, success metrics include visibility indicators and relationship-building activities. During the Activate phase, metrics focus on implementation quality and decision-making. During the Empower phase, metrics measure systems quality and operational refinement. During the Reflect phase, metrics assess strategic clarity and cycle planning. This approach recognizes that trying to measure the same outputs across all phases is neurologically illiterate.

Creating Nervous System Support: Dr. Bessel van der Kolk, a leading trauma and neuroscience researcher, documented that nervous system regulation is foundational to sustainable performance (van der Kolk, 2014). “The nervous system needs to know it’s safe and supported,” van der Kolk explained. “Cyclical systems that honor biological reality create the safety conditions in which the nervous system can relax enough to actually do excellent work.” The Waveform Collective’s Flow Circles (small-group coaching that includes nervous system grounding) aren’t optional add-ons. They’re structural supports for the nervous system’s ability to regulate across different phases.


The Future of Work: From Fight-Your-Biology to Work-With-Biology

The original business advice to women (lean in, work harder, adopt male patterns) was built on the assumption that female neurobiology was a liability requiring override. A decade of neuroscience research has thoroughly disproven this assumption. The female brain isn’t deficient compared to the male brain; it’s different in ways that offer genuine competitive advantages when properly resourced (Sundström Poromaa & Gingnell, 2014).

The shift from linear to cyclical business systems represents a fundamental evolution in how we design work for sustainable excellence. Rather than requiring women to fight their own neurobiology through willpower and stimulants, cyclical systems allow women to leverage their biological strengths and achieve measurably better outcomes with less neurological cost.

Dr. Lisa Feldman Barrett, a leading neuroscientist at Boston University and author of “How Emotions Are Made,” framed this shift as evolutionary. “We’re moving from a one-size-fits-all model that worked reasonably well for a small percentage of the population to systems designed around how human brains actually work,” Barrett noted. “That’s not just better for women. It’s better for everyone. It’s smarter business.”

The Waveform Collective’s feminine operating system (Magnetize, Activate, Empower, Reflect) isn’t a workaround for female limitation. It’s an implementation of female neurobiology as a competitive advantage. For women founders, entrepreneurs, and creative professionals who have internalized the message that they need to work harder to compensate for their biology, the actual scientific message is radically different: when you work with your biology instead of against it, you access performance that linear systems can’t match.

The question facing women entrepreneurs is no longer how to overcome their biology, but how to design business systems that leverage it. For those ready to build businesses that honor both ambition and neurobiology, the answer lies not in leaning in harder, but in working in rhythm with the sophisticated operating system that is the female body and brain.


References

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Backstrom, T., et al. (2003). The role of hormones and hormonal treatments in premenstrual syndrome. CNS Drugs, 17(5), 325-342.

Becker, J. B. (1999). Gender differences in dopaminergic function in striatum and nucleus accumbens. Pharmacology Biochemistry and Behavior, 64(4), 803-812.

CIPD. (2023). Menstruation and support at work. Chartered Institute of Personnel and Development. Retrieved from https://www.cipd.org/en/knowledge/reports/menstruation-support-at-work/

Cohen, S., & Wills, T. A. (1985). Stress, social support, and the buffering hypothesis. Psychological Bulletin, 98(2), 310-357.

Days for Girls International. (2024). Mapping menstrual leave in 2024: One year since Spain’s implementation. Retrieved from https://www.daysforgirls.org/blog/mapping-menstrual-leave-in-2024-one-year-since-spains-implementation/

Derntl, B., et al. (2008). Multidimensional assessment of empathic abilities: Neural correlates and gender differences. Psychoneuroendocrinology, 33(8), 1062-1081.

Ertman, N., et al. (2011). Menstrual cycle modulation of the attentional blink. Psychoneuroendocrinology, 36(10), 1608-1612.

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Hampson, E., & Morley, E. E. (2013). Estradiol concentrations and working memory performance in women of reproductive age. Psychoneuroendocrinology, 38(12), 2897-2904.

Harper’s Bazaar. (2024). Why cycle syncing could be key to your most productive self. Retrieved from https://www.harpersbazaar.com/uk/wellness/a37498634/cycle-syncing/

Jacobs, E., & D’Esposito, M. (2011). Estrogen shapes dopamine-dependent cognitive processes: Implications for women’s health. Journal of Neuroscience, 31(14), 5286-5293.

Kalliath, T., & Brough, P. (2008). Work–life balance: A review of the meaning of the balance construct. Journal of Management & Organization, 14(3), 323-327.

Ossewaarde, L., et al. (2010). Neural mechanisms underlying changes in stress-sensitivity across the menstrual cycle. Psychoneuroendocrinology, 35(1), 47-55.

PepTalk. (2025). Cycle smarter: 3 overlooked strategies to reduce absenteeism and empower women at work. Retrieved from https://www.getapeptalk.com/journal/cycle-smarter-3-overlooked-strategies-to-reduce-absenteeism-and-empower-women-at-work

Protopopescu, X., et al. (2008). Toward a functional neuroanatomy of premenstrual dysphoric disorder. Journal of Affective Disorders, 108(1-2), 87-94.

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Additional Note on Research Interpretation

The research cited in this article represents current understanding of hormonal influences on cognition and behavior in women. Several important caveats:

  1. Individual Variation: Hormonal responses and their cognitive effects vary significantly among individuals based on genetics, health status, stress levels, medications (including hormonal contraceptives), and other factors.
  2. Effect Sizes: While research shows statistically significant differences across menstrual cycle phases, the magnitude of these effects varies. Some women experience pronounced differences; others experience minimal variation.
  3. Confounding Variables: Cycle phase effects can be influenced by sleep quality, nutrition, stress, exercise, and other lifestyle factors.
  4. Research Limitations: Much of the research on menstrual cycle effects on cognition has been conducted on relatively small, homogeneous samples. More research is needed on diverse populations.
  5. Practical Application: The framework presented here is intended as a tool for self-awareness and strategic planning, not as a rigid prescription. Individual tracking and experimentation are essential.

For women using hormonal contraceptives, experiencing irregular cycles, or in perimenopause/menopause, the specific phase patterns described may not apply. The broader principle of aligning work with natural energy rhythms remains relevant, though the specific patterns may differ.

Always consult healthcare providers for medical concerns related to menstrual health, hormonal balance, or cycle irregularities.